Don't get me wrong, I know just how much botting goes on, but, finding runes is something different. There's simply no way that enough legitimate ber/vex/ohm/cham/sur/jah runes and the like are being found to fuel the production of all the favoured 1.10 runewords.
I've only ever heard of one person making the effort to cube guls found from hellforge all the way up to being able to make the infinity runeword, and that involved a ridiculous number of runs. So the rest are seemingly relying on lucky drops (with MF not being a factor since it doesn't affect rune drops) from the countess, those bugged chests in lower kurast or during more traditional mf runs, and I don't believe that these can account for all that's being traded.