Yes, although scientifically it shouldn't. Alcohol is alcohol!
Stella Artois always makes me super aggressive, yet Foster's or Vodka/Red Bull always keeps me mellow. Spirits generally just daze me into a stupor.
Alcohol isn't alcohol scientifically, in that sense, ethanol is ethanol in talking about drinking alcohol and yes you're right, it is the same.
The thing is since when was alcohol the ONLY substance that causes your brain chemistry to react, answer is, never.
Theres other alcohols produced in smaller quantities, for instance propanol, glycol, probably others, and theres a whole bunch of other things.
Hops is used in many natural sleep remedy type pills, and you'll also potentially have the slight effect of hops working on your brain.
The main thing is, different types of drinks, are, unsurprisingly, different.
Your body needs both good and bad cholestrol but it will react different with different ratios in the body. Thats pretty much the same for most interactions, most are effected by others.
Maybe hops has a more profound effect on a "drunk" brain than a sober one, maybe a higher ratio of ethanol to propanol produces a happier drunk than one with more propanol, theres dozens of chemicals in every alcoholic drink, ethanol is simply the MAIN brain effecting chemical, not the only one.
Then theres the other fairly simple, and not always accurate case of, people drink depending on their mood to start with.
Bad mood, want to get rat arsed, get straight on a spirit and end up in a fight. Hard days work, come home, have a glass of wine with the wife over dinner and feel naturally tired at the end of the day, do that often enough and even when you drink in a different situation your body reacts by routine and thinks its bed time soon.
Theres loads of different reasons drinks effect you differently, different chemicals, different reasons for drinking, simply being used to a certain routine.