Nevewinter Nights II.
Gorgeous character & environment graphics, but... hideous inventory graphics, clunky modelling, irritating cut scenes, aggravating character voices, nonsensical party system, and a criminally outdated "area-based" environment (unlike DS II or WoW, which has a true 3D environment).
Having played and loved all three of the original NWN series, I was hopelessly let down by NWN II. They had the opportunity to fix all the silly things from NWN, but chose to keep them in and add a few more.