The game works in Vista although don't expect to run it properly on Hardware Mode unless you enjoy seeing black bars and giltches everywhere. It pretty much has some of the same issues that plagued FFVII PC but compared to it, at least this one works slightly better.
Personally I still wouldn't bother though. Only advantage I see in the PC version is faster loading times or using save game editors and thats it. Music uses the PC's crappy MIDI sound, although you can edit it to sound almost like the PS1 version and there is no rumble pad support.