This year,
Will give
Champions Online,
04/09/2009, a try during open beta before deciding. Losing interest in mmo's, will most likely try a few like The Agency, APB, SW:TOR, Jumpgate and Black Prophecy if I get the chance though during beta's.
Wolfenstein,
21/08/2009, although need to look into the ingame gold pieces thing that an online shop mentions in the description, micro transactions to buy weapons and equipment? :/
Dragon Age,
23/10/2009, almost certain.
Borderlands,
23/10/2009, probably.
Max Payne 3,
30/10/2009, probably, need to find out more about it though just in case.
Modern Warfare 2,
10/11/2009, probably.
Looking towards next year, what should be safe sequels;
Starcraft 2 04/12/2009
Diablo if it even makes next year, same goes for SC 2
Mass Effect 2 29/01/2010
Thief 4 26/03/2010
Deus Ex 3 24/09/2010
and because I'm a sucker for interesting gametrailers;
Singularity 26/03/2010,
Brink 26/03/2010
edit: oh and the new Mechwarrior whenever that's due

Added dates from an online shop so I don't expect they're all accurate.