hmm HD...
That should never really be used to describe monitor resolutions...
HD is "high definition" i.e crisp image quality. - watching a film on a large screen with a low res is more low definition,
Monitors on the otehr hand have native resolutions for each size which provides a crisp quality image and resolution scales depenign on the size, so either way, you get HD image quality - just more of it

Rather than HD, you shoulod have said high/er resolution, or just 1920x1080
The ports shouldnt put differnt strains on the card
go for dvi/dp over vga/hdmi (hdmi is limited to 1080 and vga cant do 1080, plus the dvi/dp is crisper image quality) HDMI should mainly be used fotr connecting hdtv's to computers and is incorrectly misinterprited to be better tan dvi becasue it has HD in the name.