WoW is both a fine example of a successful mass gaming profit model and the many follies of modern game design. Frozen Synapse has also been grinding my gears recently, but not as much as various incarnations of Civ, which was always well received, but has never improved on its rather peculiar AI and shoddy end game. In fact, if 4X genre recovers any time before I hit the grave, I'd tap dance my way around the world - barefoot!
Ninja edit: Seeing FF mentioned above made me think of two things I dislike most about life - Disney and Square's fetish for it, aka Kingdom Hearts. :X