Ultima Online - poor development ruined it before its peak, unforgivable because I've yet to see an mmorpg come close to it
Theme Park - crappy follow up titles, they gave up altogether when Rollercoaster Tycoon came about - think about this one... we all remember bullfrogs Theme Park, but how many of us remember the games which followed it? (theme park world/inc etc)
Dungeon keeper - poorly supported sequel, canned the franchise altogether. Released mobile app version in light of a kickstarter projects popularity (war for the overworld)
The Sims - mainly aimed at TS3 which is buggy to the extent it relies on third party mods to solve issues developers ignore, way too much DLC (not counting expansion/add on packs)
Syndicate - they turned a unique franchise with popular following into just another FPS flop
Command and Conquer - mainly because of CNC4, but also the likes of CNC renegade which was supported very poorly (and there clearly is demand for, going from the popularity of the Renegade X remake) Even more amusing that cnc4 is usually the first title EA chuck into the £4 bargain bin when theres a sale on.. probably just so on unit volumes it looks good to say they shifted a couple million even though the game was ****
Just a handful of examples from EA but theres plenty more where those come from.. not to mention the multi-kill effect when they buyout a studio for the sake of 1 or 2 franchises and lock all the other works/IP's away to rot because they are profitable, but not profitable enough.
In reality however you'd be hard pressed to find a company that didn't sin on its followers in some shape or form, even the most successful ones, and it also comes down to perspective of the consumer
I can't believe they destroyed C & C then didn't even release it, I still go back to Red Alert and wonder why no one has tried to recreate it 20 years on!?!?!?!
Have to get permission from franchise holder first.. they might had shut down the franchise but still hold rights, even the Renegade X creators had to ask first