I know I may be courting flame throwers here but why would it matter? APU's are a budget option, they combine a weak CPU with a weak GPU, who the hell thinks to themselves "well I don't really want to spend any money on a decent CPU or GPU, but I must have an add in PhysX card!".
If a person has an APU and an Nvidia GPU because they decided they needed more GPU grunt than the APU could provide then common sense is to disable the redundant iGPU anyway so the PhysX lock wouldn't even matter.
The Metro and Borderlands series are night and day better with PhysX, to the point I choose to play those on my GTX780 rig instead of my CF R290 rig.