Account departments are often sent emails will invoices attached as .pdf files.
How does one stop this?
If one scans the attachment or email will this be picked up upon before opening?
Asking as we legitimately want some sort of defence, half these crypolockers are reported as zero day variations.
You can't really prevent them. Antivirus will only pick up known ones or ones written using similar techniques to known ones. Theres always going to be some that can slip past even the best AV.
IIRC Adobe pro reader has an option to prevent any executable embedded code from running. Cant remember how much the pro version costs though.
Probably the only way short of a whitelist of email address(which can be spoofed or maybe the incoming email is compromised) would be to move to another less user friendly attachment form. Or sandbox the users PC's from the network.