Id just go for it to be honest.
Just need to make sure that you dont only have a 120mm space, but also enough to fit both the radiator AND the fan into wherever, plus the hoses need to be long and flexible enough to go from the CPU to where they will go into the RAD... In 90% of the time you wont have any issues, but just in case...
For example, a couple of system I knocked up for myself lately, were with ITX... I bought a Global#Win 130 from the MM here and that takes coolermster Seidon 120 and so I bought one of those AIO coolers. The Mobo and CPU are AMD A10 and the gap between the CPU and the PSU was really small and so a, AIO was the perfect choice, plus the 120mm at the front of the case also gave enough spec to fit the Radiator and the Seidon 120 was the PERFECT choice for that Case.
Then a week of so later, I saw another case, but this was a globalWin 120 and i nwhite and of course because I liked that 130, I jumped at this one, and anyway, while I was waiting, I went out and bought another Seidon120... however it turns out that the Seidon will not fit the 120 case... No AIO will, there is simply not enough room.
GUTTED!
So, Im using a very small cooler wedged under there that is only just doing enough of a good job to make me not worry for now... I dont use the thing so its only going to be dumped with all the others, but I would liek to know its right by the tim I am through.
The AMD A10 setup with the Sedion is so sweet and cool, that I have decided to use it as my main Linux PC.
Now, as another completely lame excuse so I can waffle on like a mental patient, but the other week, I wanted to upgrade my AMD 8350 to a 9590 and I bought the CPU, but the Apfenholm AIO setup that I am using on that simply didnt do a good enough job.
I bought a Noctua HN-15 and I decided that it was simply far too heavy for me to feel comfortable with it. I then decided that the only way I can be madeto feel better and to use such a stupidly heavy cooler, was to have the Mobo lie flat and look for a case that will do that for me... My Media PC is based on the Zalman and that does it, but it is not quite high enough, but I ended up buying the Thermaltake Core X9 Snow edition, and when that came, I realised just how friggin big it was.
I then realised that I have been going weird buying so much rubbish, and I will not be actually getting any better speeds on the AMD because the 8350 is running at 4.7 anyway, so I ended up getting rid of all thse bits that I have just splashed out on.
But the fact is, that the Alpenfhon or whatever the hell it is, is one of my best 120mm AIO coolers and it is NOT as good as the Noctua NH-15.
Actually, I also got a cheap and Nasty CoolIT AIO Setup that only cost me £29 and thats on my I7-980 PC and thats keeping that absolutely stone cold so that might have been a better AIO to try on the 9590 to be honest LOL
ok, that will do.
Anyway, ignore everything I have said, just get an AIO setup for the giggles they ARE fun.