I've only recently completed Mass Effect 2 and I was left frustrated by the fact that your squadmates lives aren't really in your hands in the final battle. Annoying if you want to get the trophy/achievement on your first playthrough. I had full Paragon but for some reason Miranda's Paragon conversation choice was never selectable, so she died in the final mission in a cutscene completely out of my control. Also, randomly, Jack died in one of the very first scenes which was annoying to say the least as Miranda died due to me losing her loyalty for siding with Jack in an argument. :/