I think so, i have a feeling it could be my PSU, it makes a loud screeching noise and doesn't shut up but if i shut down it stops. I was ocing when it was quiet left fur mark running for 3 hours at 1200mhz memory and it was fine. I then tried it at 1205 mhz for 15 minutes fine again, but during the duration of the benching the psu started to scream again but it didn't crash. I then upped it again to 1210mhz and it crashed straight away so i went back to 1200mhz (stable) and it crashed immediately also.
atm i'm trying 725/1210 with a quiet psu after a restart and it hasn't crashed yet.
EDIT: Also my card is a reference card.