Alfie Clamp stuns doctors after being born with extra strand of DNA

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A BRITISH toddler has become the first person in the world to be born with an extra strand in his DNA, in a condition so rare doctors don't even know its name.

Alfie Clamp, from Warwickshire, northern England, has a seventh chromosome which has an extra arm.

Doctor discovered the extremely rare condition when Alfie, who was born blind and with severe disabilities, was just six weeks old.

A series of tests revealed the extra strand of DNA, which has left the medical world baffled.

His parents, Gemma and Richard, and doctors have no idea what his life expectancy will be or whether his condition will even improve.

The little boy has digestive problems, needs drugs to help his body absorb nutrients and suffers fits sparked by high temperatures and metabolic problems.

And in his short life he has been rushed to hospital six times after a series of problems, including stopping breathing.

But his parents said despite his ordeal their son means the world to them and are now concentrating on the simple things, the Daily Mail reported.

Mrs Clamp said: “When the doctors told us I was absolutely devastated. As a pregnant mum you spend nine months thinking about what it will be like when your baby takes their first step or claps their hands.

“Having a boy like Alfie makes you appreciate the little things. He didn't roll over until he was 18 months old, but we were so excited when he did.”

Read more about Alfie Clamp born with extra DNA in world first and see a picture of him at the

http://www.news.com.au/world/brave-...ra-strand-of-dna/story-e6frfkyi-1226037698646

Its amazing that something so small and minute with such a small chance of happening can cause such debilitating problems. But yet at the same time is very intriguing, what would happen if all of them had an extra arm? And so on.
 
Alfie Clamp, from Warwickshire, northern England, has a seventh chromosome which has an extra arm.

Warwickshire is NOT in northern England! I've never been so offended in my life :mad:
 
Would be interesting to see what the code making up the "extra arm" actually is. My bet is its a copy of the opposite Q or P region which it was paired with, yet this is pure speculation until proper information is released detailing exactly whats gone wrong.

Genetic disorders that copy chromosomes or regions of them aren't exactly rare, with down syndrome being the one most people are aware of with the copying of chromosome 21. Theres a lot of gender specific genetic mutations with copying or X or Y chromosomes (giving 3 instead of 2 etc) as well which most of the general public just aren't aware exist.

From reading the article, I don't fancy the kids chances if he has serious metabolic problems are some of the most difficult to treat long term.
 
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I never said I didn't believe the initial story, just that I think the terms and general science in the article were dubious.

This condition is called Partial Trisomy 7. It's not 'so rare that it doesn't have a name'.

DNA is double stranded. For it have an 'extra strand' implies it's now triple stranded. Hydrogen bonding within a DNA molecule allows for bases to pair into a helix. It's a two-way event and inherently cannot occur any other way.

Google Scholar.
 
I understand that we have 46 chromosomes including X/Y and already mentioned by James J about trisomy 21 (or 8 or 13). In relation to the 46, what does it mean though to have an extra strand of DNA?
 
I understand that we have 46 chromosomes including X/Y and already mentioned by James J about trisomy 21 (or 8 or 13). In relation to the 46, what does it mean though to have an extra strand of DNA?

He has an extra fragmented copy of a chromosone. "Extra strand" is entirely fallacious.
 
Man I thought he was going to have a triple helix, now that would be something new!

However he just has an dodgy chromosome 7 with an extra bit and is none the better for it, boring.
 
I never said I didn't believe the initial story, just that I think the terms and general science in the article were dubious.

This condition is called Partial Trisomy 7. It's not 'so rare that it doesn't have a name'.

DNA is double stranded. For it have an 'extra strand' implies it's now triple stranded. Hydrogen bonding within a DNA molecule allows for bases to pair into a helix. It's a two-way event and inherently cannot occur any other way.

Google Scholar.

There can be triple stranded DNA but its mostly in bacteria circular DNA with the addition of viral DNA being "spliced" into it. Its creation is extremely brief also.

I hate the way that news articles cannot define what they actually want to say in any scientific detail. It does read that the child has a triple helix structure to its DNA though which is just retarded, especially when they are referring to an extra copied P or Q arm of a chromosome.
 
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