stainless steel will way a ton, but if you're designing your own case... you could design the panels you want on AutoCAD... nest them all together, take the disc to a laser cutter and get the whole lot done in one go... any custom design you want.....a laser will cut it accurately in about 5 mins..... i used to be a laser profile cutter.
best material 2mm ALLY... but be careful of highly polished/ mirrored S.S/ALLY, because the laser bed might scratch it....it's far too easy to scratch anyway.. go for a brushed/ sandblasted type of finish.
the laser will cut all your screw holes/ fan holes/ window in side panel etc...any crazy design you want as easy as pie....it'll be expensive though
you'll only need 6 panels, and some kind of internal frame, all of this can be nested up on one sheet and cut out of 2mm ally..to save cost, do not choose different mat'l thickness.... whack it out in one go.
http://www.yorkshirelaser.co.uk/
i've just had a thought..... you can custom build a better version of the Antec Skeleton by laser profiling, it'll look flipping fantastic.............you can get the top fan from them too!
you could design a retro ``bird's nest style``.. or just copy theirs and increase the dimensions by 2'' in every direction... no problems with cooling whatsoever ...the laser will cut out any fancy pants design easily.... this way, you can fit any size of CPU cooler you like
just design good slide out trays for your mobo and below, another similar tray for everything else..... you'll need a couple of 120 mm fans at one end for cooling this lower tray..... but flipping heck... it's dead easy.
right, i've got the Autocad disc; i'm going to reupload it.... this needs a new thread...Mal's Skeleton

