I used to use Sabayon... as already said, it's a gentoo-based distro.
Can't help with wireless as I used it on a PC that's hooked directly into a router. However, it was a cinch to get my Nvidia graphics card working under it (was still using a 6600GT at the time, iirc). I think it might have even been enabled without me needing to do anything at all.
There were a couple of niggles I had with Sabayon... getting my USB keyboard and mouse to work correctly was tedious. The mouse was very jerky, whereas the keyboard was like it was on speed so typing anything was impossible
sssssssssssshhhhhhhhhhhhhhhuuuuuuuuuuuuuuuuuttttttttttttttttdddddddddddddddddooooooooooooowwwwwwwwwwwwwwnnnnnnnnnnn ---------------------hhhhhhhhhhhhhhhhhhhhhhhhh nnnnnnnnnnnnnnnnoooooooooooowwwwwwwwwwwwwww
...that sort of thing.
Support was much more personalised than the bigger distros. I remember getting some help directly from the main guy responsible for it, which was pretty cool. Other than that, the official forums were slow to respond to my questions.
Not a bad distro overall, but I've been converted to *buntu due to its high user base.