ATX Case and ITX Motherboard

most of them will - as long as the standoff are removeable it should have positions for all smaller mobo sizes.
A few of the cheaper punched steel cases don't - but the description on OcUK website / manifactures site will tell you

but why put a tiny board (that usually costs more that it's ATX big brother) in a overly large case? Temp solution / second hand mobo?
 
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mini itx uses the 4 standoffs in any atx case on the top left. it should fit in any case atx or matx ive currently got mine in a corsair 700d looks really funny but its the only case I have, could really get another 3 itx boards in there
 
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