The mATX boards can still retain most of the same functions, exept you are les likely to find sli/xfire on a mATX board, however there are some that can do this. So essentially if you find the right mATX board it is possible to have all the same functions on a smaller size.
Not sure on OC ability, i would reccomend searching review sites for a mATX board review.
Also in terms of sli/xfire the full ATX boards can have more spacing between the gfx card slots for better airflow.
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in terms of the asus pro board i posted and its full size brother there are a few less connectivity ports on the mATX, like slightly less sata and esata ports, and no front usb3 header connection etc.
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