hmm. 333/266= 1.25 or 4:5 multi
so you'll need 320 FSB to hit DDR2-800 on the DDR2-667 setting. That'll Oc you E6300 to 2.25Ghz or thereabouts, which it should do easily.
I maxed out my DUAL-VSTA at 301 FSB, not sure how the 4Core does though, and watch for the memory voltages, as the DUAL-VSTA gave 2.0Vdimm on its "High" setting, and some DDR2-800 needs more than that.