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[garyh]

Do you mean one that is network enabled? or one that scans other logical disks on your local machine - if it's the latter, what's the point? The registry settings and temp files are by default stored on the Windows drive?

 

[knowlesy]

http://lifehacker.com/397792/five-best-windows-maintenance-tools

this link should give you a few ideas and read the comments too it has a few there

 

[jbloggs]

Have a look in the Registry/(Unwanted) Data Removel Software section...

CCleaner is hard to beat to be honest....