Question: why disable the Windows Firewall? It works nicely and would just give an extra layer of protection along with your Comodo.
I'm running McAfee Host Intrusion Prevention, Zone Alarm, and Windows Firewall on my work PC (because they're nuts!) and have never had any conflicts. Just a few more confirmation prompts when I attempt to use a new application that needs access.I thought it was a bad idea to be running more then one firewall as it could cause conflicts.