So it's about trying to find the sweet spot.
We are all being increasingly told to save the environment. When DC stuff first came about it was trying to use spare computer cycles. Now as things are more efficient, if the PC is less used, everything throttles back. Folding, BOINC, etc works against that efficiency. For some projects like trying to find aliens, perhaps the environmental concerns can't override the science, If you are searching for solutions to health, DC can be more beneficial.
I suppose I need to get a power consumption meter so I can try and decide at what level of overclock in folding is the most rewarding for PPD versus power use, and that changes for different PC configurations.