Not SETI but I have run 2x5970 and currently have 2x6990 on Milkyway. I find they use less power than single cards, even at the same clock speed. The 5970s were ok to cool on air but the 6990 were a nightmare. Even with the fans on 100% they were hitting 100C and I could still hear the fans through 3 walls They are now watercooled and totally silent as well as 50C cooler In my experience more than two GPUs in one system, regardless of whether you are using single or dual GPU cards, is about the limit for air cooling and things get very loud and hot if you put more than that in.
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