Quick calculation for 4ghz would be 380fsb with multi @ 10.5, or 400fsb if u use 10 on the multi..
So if the cpu dos'nt have a fsb wall, and your mobo can go that high, i don't see it should'nt hit 4ghz, but again all depends on how much voltage would be needed, allways best to stay under 1.4v.
Quick research on the mobo, states it officially supports 333/1333 fsb so thats no problem, and will supported 400/1600fsb via overclocking.
So when u go over 333fsb you would have to up the north bridge volts abit too.
So your deffinatly looking at an easy mid 3ghz maybe more depending on voltages, and ofcourse all cpu's are diff.