I need some similar advice with my e8400.
It sits in a P5Q se2 next to 2x2gb 1066mhz dominators.
It passed 24hrs of prime95 at 3.6 but I have not adjusted any of the other voltages apart from the vcore. I would like to get it to 4ghz but last time i tried it one of the cores failed prim95 after 7 hours(the other was fine). Also one of my cores tends to run 3-7 degrees hotter than the other; is that normal?
One other thing to note, I am running my memory on 1:1 (800mhz) because when I put it up I had 'shutdown issues' which ment basicly my system would not fully power down and I have to hold the power button for 4 seconds to make the fans etc stop spinning. Not idea why this happened but I gave up trying to fix it and just had slighlty slower ram.
my case is raven02 and cooler is freezer 7 so cooling should not be a problem.
Any advice on what to do or even where to read up on chipset voltages would be a huge help.
Memory at 1:1 is fine, but you should hit 4GHz no problem. That hot core is probably down to the cooler not being seated correctly, but they're never perfectly even. 7C is a bit more than I'd be happy with though. What Vcore are you running at now, and what was it at for your 4GHz run? I'm at 4.25GHz at 1.328V so you shouldn't need a huge amount for 4GHz

that's nothing to worry about ...or if it is, I haven't been!! lol