It will fit at the front but possibly not at the top as there is only clearance for a
40mm radiator + 25mm fan ( mine was hitting the motherboard ), I ended up switching to a cheap 30mm radiator for the top with that case
A thick high fpi 280mm radiator at the front works well with the 450D, however availability of good 140mm fans is a problem, I was using noctua industrial ppc which were very loud at high rpm.
Predator is nice though I would recommend it