I am getting seriously annoyed with Fallout 3 now, suddenly the game decides to crash whenever I save or enter a building 
These are the things I have tried so far without success:
- Run CPU and GPU at stock
- Install the v1.1 patch
- disable mods
- trying older saves
- install Nvidia 182.50 drivers instead of 182.06
None of these fixes work, what else is there to do?
I am considering reinstalling from scratch but what should I backup to be able to continue where I left off, just the saves, do they also hold data on level and collected stuff?

These are the things I have tried so far without success:
- Run CPU and GPU at stock
- Install the v1.1 patch
- disable mods
- trying older saves
- install Nvidia 182.50 drivers instead of 182.06
None of these fixes work, what else is there to do?
I am considering reinstalling from scratch but what should I backup to be able to continue where I left off, just the saves, do they also hold data on level and collected stuff?