Games flickering on left mouse button click. Video included. Seemingly a hardware fault somewhere.

[Valkorian]

https://www.youtube.com/watch?v=HPTHoGq7gks

This has persisted over 3 monitors, brand new HDMI and DP cables and this was taken on my new 7800XT card that replaced a 3070. So totally different driver sets with a brand new Windows install and it still happens. Also persisted over replacing the PSU.

The video is recorded from my phone because recording the screen doesn't show it, I'm thinking by process of elimination it's a motherboard issue, but I want to see what people who know more than I do think.

 

[FredFlint]

Does it happen in windows or other games? I would try a different mouse, it’s unlikely to be a motherboard issue although it could be a USB problem so try moving the mouse to different USB ports. If you are using software that came with the mouse, that could be a problem.