I'm in Reading, can see the 3 guineas from my desk right now. Bit of advice, avoid it like the plague

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Quiet beer no chavs go to The Blagrave Arms (nr station) or Coopers Arms (nr market Square). Both kinda old fashoned, never get too busy - good for decent beer and a chat.
Lively, go to Purple Tutrle (Gun St). Young, loud, alternative. Open late.
Different, go to Afrobar, nr the station (the upstairs portion of a very good sandwich shop called Chan Chams) - the owners\girls working there are really really nice.
Good food go to Corn Stores (aka I'll Gusto) (nr Station), Sweeney and Todd (awesome pie shop\bar) or The Bell and Dragon nr forbury shops and on the Kennet - excellent food ($$), great location but a little walk from town - highly recommended, excellent in summer.
Avoid at all cost;
- HoneyPot (dodgy strip club\bar), think it's closed no tho
- Nags Head (oxford road), always full of crazy old irish men and other undesirables- likely to get mugged\bummed in toilets.
- Wynford Arms (gay bar...apparenetly...)
- Usual rubbish chains - Monk's Retreat, Cafe Du Sport....list goes on...
- personally I don't like the Oracle - it's a little too 'clinical', no soul.
Or see,
http://www.readingpubs.co.uk/
Edit: Another vote for Hob Goblin and Rising Sunn.
EDIT AGAIN: Reading Pub Crawl!!!!
Skidd.