EZBackitup is great.
Like Synctoy it doesn't compress the data or anything like that, it just copies everything over like a mirror. It means that you'll need a big backup drive. If you back up two harddrives with 80GB of data on each, you're going to need a 200GB+ backup drive, however storage is so cheap these days, you can get 750GB/1TB drives without breaking the bank.
IMO it is far more reliable than utilites that compress your data, not only do you not run the risk of the compressed file becoming corrupt, but you don't have to uncompress it all to restore one file.