since its a corsair H50 your using i'll disagree with the in at the front out at the back, because having the H60 as an intake is far more efficient. all i'd do is flip the front fan around so its an intake. positive pressure is far better than negative for keeping the case dust free, and having the front as an intake will get more cool air for the graphics cards
also, is there any room behind the motherboard or DVD and HDD cages for some of those cables?