The benifit of a 1:1 ratio is that it is easier for the motherboard to run stable, as it does not have to synthesize an extra clock for the memory, when overclocking my asus p5n-e sli, setting the memory to 1:1 allowed me to reach a higher fsb, due to the increased motherboard stability.
Additionally, due to the architecture of s775 systems, you do not gain much performance ofer 1:1 due to the fsb becoming the main bottleneck.
Depending on how your motherboard behaves it may be easier to use a memory multipler or drop the multiplyer of your cpu to achieve higher fsb and memoryy clocks.
To be honest each computer setup is different, not all chips are created equal, and you need to experiment to find the max overclock you can achieve.
First, you need to find the max fsb of the motherboard, deduce the cpu multi and the ram to 1:1 and raise the fsb till you find the top limit.
second, find the max ram speed, increase the ram multi and raise till your computer becomes unstable
third drop the ram to 1:1 again increase the cpu multipler to max and raise the fsb till you find the max oc for the cpu
fourtch, armed with this information, try different combinations of multiplers for ram and cpu to get the max ram, fsb and cpu frequency possible
you can use something like orthos for stability checks