This is the thing, I know nothing about what's good/bad, compatible/incompatible & bottleknecking etc. All I know is how to plug things in and install software xD
If I remove the things I don't from your list I get the price down to £1,268.81. That's £732 under my budget. Plus I'd prefer not to have a water cooler unless it was strongly recommended.
I know what you mean by building your first rig, but if you look at the step by step guide thats posted at the top of the forum.... the sticky.... then its pretty much simple.
Most of the items like motherboard are the ones that are highly rated in all the other topics in hardware.
The water cooler posted is not what you think. Its basically a plug and play. No maintenance. Its all one piece. You just forget about it and let it do its job.
Would you be comfortable doing a WC loop? Could make it super quiet that way! And should fit in budget.