Mouse & Kb for most games.
I am annoyed with remapping buttons, so when the gamepad isn't set up correctly from start like ps3/x360 controls then I think ''sod it''...
I prefer keyboard too for fighting games, I only play some games with the pad, stuff like Devil May Cry, Sega Rally Revolution, Geometry wars, Footy games, etc... I often try giving ''couch'' gaming a go but usually end up swearing due to the controls or not being able to control everything with the pad correctly ( eg. TDU2).
If a game works correctly out of the box with a directimput pad without having to remap everything I try playing with the pad. Some 3rd person adventure games eg. Tomb Raider I play with a pad too.
But shooters, strategy, fighting games, and most driving games, mouse&kb>anything.