The G43 G3's have a locked cpu voltage adjustment, and therefore only allow 'Auto' in the bios. This results in a more generous application of voltage when overclocking, but I've never seen mine go above 1.36 at 4.5ghz.
This post has excellent information for overclocking an MSI board;
http://forums.overclockers.co.uk/showthread.php?t=18340310
but be aware that the G43 series are a budget z68 mobo, and they have less features than the more expensive boards. That being said, I've been very happy with mine for the price. The build quality is solid and the number of USB & SATA ports acceptable for the price. The bios are easy to setup, and the windows based utilities and bios tool are also straight forward.
If you can't be bothered with faffing about in the bios, the OC genie function works without issue, but to only a 4.12 ghz maximum. It will also disable all power saving features, and therefore consume a lot more juice at idle.
Also be aware that these boards are only a single GPU board, even though they are advertised as crossfire; the second PCIE slot runs at too slow a speed to be a viable option imo.
Another possibility for a good budget z68 mobo would be this one;
http://www.overclockers.co.uk/showproduct.php?prodid=MB-364-GI&groupid=701&catid=5&subcat=1990
This board has a manual cpu voltage adjustment, and a traditional bios. Othwerwise the features set is similar to the MSI, and indeed the Asus entry level z68 board. Due to the manual voltage adjustment, you may well see a higher overclock than the MSI. Of course, altering the voltage manually in increments will allow you to set a higher overclock at much lower temps than using an auto setting.
I personally had to try 3 of the gigabyte boards before going for the MSI. But I'll put that down to my own bad luck, as I've always had good Gigabyte mobo's in the past. The z68ap-d3 has been given rave reviews by a lot of people, and must therefore be worth putting on your shortlist.