No, whoever told you that is a complete tool, in most gaming situations theres very little difference, the only times you'll see the difference will be in non gpu limited situations, the whole point of getting extra gpu's, is to run a heavier gpu load, so the question remains, why aren't you running at your gpu's limits, if you've paid for them. Answer is, you don't, no matter what GPU setup you have you'll be basically gpu limited.
IF you have a 4350 and game at 1024x768 with low settings, you're gpu limited, if you run a 5870 at 1920x1200 at high settings, you're gpu limited, if you run a triple sli or quadfire set up, you'll likely be using a 30" screen, or with AMD these days, eyefinity and a humougous res, and therefore again be gpu limited.
You'd notice a difference between a P2 and an i7, if you run 4x5870's at 1680x1050, but why would you buy 4 gpu's to run that res?
I've seen one review to date suggesting you MUST have a i7 for crossfire, it used a i7 quad, against a penryn based DUAL CORE< and called it a fair test but argued the increased performance was all down to architecture, and how SLI/xfire simply worked better with the new architecture.
ANy sane testing and you'd see little to no difference, in all but the most rare and obscure of titles.