Police have surrounded a man inside a car in Birmingham city centre with "canisters" surrounding his body and his hands bound.
Fire crews, an Army bomb disposal team and negotiators with West Midlands Police are at the scene in Saltley.
Ch Supt Tom Coughlan said it was unclear whether the man was conscious and whether he was there of his own accord or was a victim of crime.
A police cordon has delayed trains at the city's New Street rail station.
Some people have been evacuated from their homes and were being offered shelter at Saltley Leisure Centre by the local authority, police said.
A no-fly zone has also been imposed over the immediate area.
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