Basically I have a lot of data saved in notepad (.txt) files and I want to read these into Matlab and store them in one giant matrix. Now here is the problem, the columns of data are separated by commas and colons, I have found a function to read data which contains commas but it still gives me an error whenever it encounters a colon in the .txt file, so does anybody know how I can read this data into Matlab and store it into a giant matrix?