4 is the theoretical maximum, but for this you need:
- 4 Graphics cards with the correct number of crossfire/SLI connections (for example, the new 960 can only be run in 2 way SLI since it doesn't have the physical connections for 3 or 4 way)
- 4 PCI-E slots with 16x physical dimensions, and at least 8x electrical specs on your motherboard. Spacing is also key, since most GPUs occupy 2 expansion slots.
- A capable CPU - Mainstream CPUs do not support 4 way SLI/Crossfire without additional chips on the motherboard
- A power supply with adequate connectors
And of course a big case with plenty of airflow.