please delete
He tried UEFI mode and it worked.
EDIT: Thank you for the post!
Basically it was all working fine, keyboard, PS2 mouse I believe, he did a windows update then nothing worked beyond the bios. No mouse or keyboard type/combinations worked after the BIOS. After much swearing on his part, changing a setting in his bios to UEFI mode as opposed to legacy devices I believe appears to have resolved the problem.