Depends, mSATA is very compact. Great for small builds like my pet project at the moment a small NAS server where the mSATA will hold the OS only. Some ATX gigabyte boards have mSATA connectors and intel or zotac mini-itx boards.
It's fairly pointless in a tower build, your better off just sticking a ssd in.
Good for htpcs, servers and the like. Not really sure why they include them on ATX boards.
You will probably loose one on of the SATA ports if you use mSATA and it doesnt realy have any advantage over a standard ssd and a standard ssd will probably be the cheaper option.
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