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Can't comment on 4 k but just to give you an idea- at 3440 1440p ultra and all settings on max, lowest i get is 62fps. Assume you've turned off aa. Probably about right, I do find i get higher than average cpu use in this game and it's one of the few games that occasionally throttles my card a boost or two.Got some disappointing news...Mass effect Andromeda has now officially surpassed my card, struggling to obtain 40 fps at 4K on Havarl with all the shrubbery with my MSI armor overclocked to 2Ghz. What fps are you chaps getting with your 1080ti at 4K on mass effect?