performance tweaks on a already fast system

[smogsy]

i have Vista 64bit and my pc is fast. im just wondering if i can do anything to help?

i have been using all windows built in defrag/cleaner

i used to use CCleaner/Perfectdisk on XP are they any good on vista?

pc spec is
I7 3.6Ghz 6GB 1333mhz 280GTX SLI

 

[smogsy]

i went in to system performance hit optimize for best performance big difference, i then just enabled basic vista skin back on and it flys dropped ram usage by 5% to.