Premier inn london

I would say that Euston would be easier the easier public transport commute to the places you mentioned

Warner Bros - 1 stop on train from Euston station
Leicester Square - 3 stops on tube from Euston station
London Eye - 6 stops on tube from Euston station
 
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I'd favour Euston over Paddington based on those attractions, but not enough of a difference to not just go with whatever is cheapest/closest to your terminus in london.
 
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