Quick help needed urgently!!! System file missing/corrupt!

[Wizard Keyaz]

I have this error message and can't open the computer, any suggestions on what you can do?

Here's the error message:

Windows could not start because the following file is missing or corrupt \windowssystem32\config\system. you can attempt to repair this file by starting windows setup using using the original set cd rom. select R at the first screen 2 start repair

Can you do this without the CD?