RAM For Server (6x8GB or 12x4GB?)

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Hi,

We are looking at getting 48GB of RAM for a server and was wondering if it is better to get 6x8GB or 12x4GB? Are there any benefits for having less RAM modules or more RAM modules at all for performance of the server etc.?

What would be the benefits and draw backs of having only 6 Modules instead of 12 and 12 instead of 6 Modules?

Thanks.
 
The server is a Dell R610 with 2x Xeon X5650's with 12 Memory Slots.

We currently have 12 x 2GB UDIMM's and CPUz says it is running in triple channel.
Should we be looking at getting RDIMM or UDIMM?

Is there any performance difference between the UDIMM and RDIMM? I believe i read that UDIMM only supports up to 48GB and RDIMM is up to 192GB... Is this true?
 
The manual doesn't show a 16GB memory configuration but should 16GB still be supported by the motherboard?

Also would it be possible to run 4x16GB or 8x8GB (as an example) in dual channel instead of triple channel configuration?
 
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