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Hidden & Dangerous 2: The best WWII shooter I've ever played. large open, free roam maps that let you choose tactics instead of playing on rails like most other war FPS games. The ability to play with between 1-4 in your group made it highly replayable.
UO2
DAOC2
I would so love a DAoC 2. I presume EA own the rights now so it's not out of the question as a future title. Imo it's still the best open world PvP MMO system out there.
I'd love a 2D sequel to Abe's Exoddus.