Ah, you have Mordaunt Shorts. That changes things slightly.
The idea of nominal being an average isn't strictly accurate, but trying to explain the complexities of how the impedance above the resonant frequency of the speaker is usually given as the nominal impedance doesn't really make much sense in a quick description.
I think what MS are trying to do is present their impedance figures in the best light they can. The lowest impedance for their speakers is 4 Ohms. This will probably coincide with the speaker's lowest frequency. As the frequency increases and goes through the speaker's mechanical resonant frequency the impedance will peak and then drop again. This lowest point after the mechanical resonance is the 8 Ohm nominal. As the frequency continues to rise so does the impedance. So that's where the 4-8 Ohm rating comes from. They're being honest with their ratings but it does cause some confusion when other manufacturers would quote 8 Ohms for the same impedance plot and presume that the amp could cope with a dip to 4 Ohms.
So, the question then remains, what do you set your amp on. Correct?
Partly that depends on how good the amp is at delivering current and whether you'll regularly try to max it out. A lower setting (4 Ohms or 6 Ohms) will limit the current delivery and rein in both the dynamic range and maximum volume. But you would probably only notice that if regularly running at high volume on the amp, say -10dB~+10dB. It also depends whether you decide to treat the speaker as if some other manufacturer measured it. They might have stuck an 8 Ohm Nominal label on the back. My gut feeling is to go with 8 Ohms as that's typical for other speakers that would dip to 4 Ohms too.