The only thing I can think of is your memory timings. I'm not really clued up on Core 2 Duo so I'm not sure whether that's normal or not with relaxed timings.
The optimal FSB is 450mhz. It may have a relation to ram timings. So Ram at 486 could actually be slower than ram at 400mhz. It could be a combination of timings, FSB and raw MHZ.
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