System interrupts go wild from cold boot.

try unplugging all usb connected devices except keyboard/mouse

power up PC see if it still happens

If it doesn't then power off and add one new device and power up PC , repeat until the problem device shows up
 
Think I've got this solved.

Just in case somebody does a search and ends up here. The answer for me was disabling Windows fast boot. The hibernation aspect of fast boot mode obviously played havoc with reloading drivers. Resume from hibernate would also result in crazy system interrupts.

This has done my head in for weeks and weeks. So happy to get it sorted, sleep efficiency seems to have improved too, from just under 2% drain per hour to 0.5% per hour.
 
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